Comparative Study Of Outcomes Between Holmium Laser Enucleation Of The Prostate And Turp In The Management Of BPH: Original Article

Junaid Jamil Khattak; Zakir khan; Shehzad Rehman

doi:10.64911/br59kk58

Authors

Junaid Jamil Khattak Assistant Professor Muhammad Teaching Hospital Peshawar Author https://orcid.org/0000-0002-4205-8281
Zakir khan Senior Registrar Muhammad Teaching hospital Peshawar Author https://orcid.org/0000-0002-8305-755X
Shehzad Rehman Senior Registrar, Muhammad Teaching Hospital Peshawar Author https://orcid.org/0000-0002-9262-8430

DOI:

https://doi.org/10.64911/br59kk58

Keywords:

TURP, BPH, outcomes, HoLEP

Abstract

Background: Benign Prostatic Hyperplasia (BPH), a condition that affects men during their aging process, is associated with symptoms related to the urinary tract. Procedures such as Holmium Laser Nucleation of the Prostate (Hole) and Transurethral Resection of the Prostate (TURP) provide substantial symptom relief through surgical approaches. The safety and efficacy of these treatments continue to play a central role in the choice of management.

Objectives: To compare the clinical outcomes, complications and times to recovery after Hole and TURP in management of BPH.

Methodology: This study was conducted as a prospective study at Muhammad Teaching Hospital, Peshawar, from January 2023 to January 2024. Patients with benign prostatic hyperplasia (BPH) presented for holmium laser nucleation of the prostate (HoLEP) and transurethral resection of the prostate (TURP) were included. In this study, we evaluated short-term clinical outcomes, specifically symptom relief after the procedure, complications, and duration recovery periods. In this study, we used the t-test and chi-square test, with significance defined as p < 0.05.

Results: One hundred patients have been surveyed (75 per group). Participants were aged 65.2 years (SD = 7.4). HoLEP exhibited less rate of complications (p = 0.01), reduced catheterization duration (p < 0.05) and quicker recovery (p < 0.05) in comparison to TURP. TURP patients had increased bleeding and hospitalization times. Significant improvements were recorded in the urinary flow in both groups.

Conclusion: HoLEP has been associated with better safety, faster recovery, and fewer complications than TURP especially on larger prostates with promising alternative in the treatment of BPH.